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Table 6 The pvdhfr/pvdhps genotypes and therapeutic responses of 15 patients from Tsiroanomandidy (Madagascar, 2006) treated with sulphadoxine-pyrimethamine for P. vivax infections

From: Plasmodium vivax dhfr and dhps mutations in isolates from Madagascar and therapeutic response to sulphadoxine-pyrimethamine

   Sequence polymorphism in   
Patient pvdhfr Pvdhps No. of mutations in the 2 genes Therapeutic responseb
Trial no. Age (Years) 33 58 117 383   
VIV7 2 P S S A 0 ACPR
60446 2.5 P S S A 0 ACPR
VIV14 7 L S S A 1 ACPR
VIV18 13 P S S A 0 ACPR
60756 42 P S S A 0 ACPR
VIV3 12 P R N G 3 ACPR
VIV8 34 P S N A 1 ACPR
VIV20 9 P R N A 2 TF
62298 5 P R N A 2 ACPR
60250 6 P R N A 2 ACPR
60149 8 P R N G 3 ACPR
VIV4 30 P R N G 3 ACPR
VIV12 6 P R N G 3 TF
62079 0.8 P R N A 2 TF
VIV15 2 P R N A 2 Reinfection or relapse