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Table 6 The pvdhfr/pvdhps genotypes and therapeutic responses of 15 patients from Tsiroanomandidy (Madagascar, 2006) treated with sulphadoxine-pyrimethamine for P. vivax infections

From: Plasmodium vivax dhfr and dhps mutations in isolates from Madagascar and therapeutic response to sulphadoxine-pyrimethamine

  

Sequence polymorphism in

  

Patient

pvdhfr

Pvdhps

No. of mutations in the 2 genes

Therapeutic responseb

Trial no.

Age (Years)

33

58

117

383

  

VIV7

2

P

S

S

A

0

ACPR

60446

2.5

P

S

S

A

0

ACPR

VIV14

7

L

S

S

A

1

ACPR

VIV18

13

P

S

S

A

0

ACPR

60756

42

P

S

S

A

0

ACPR

VIV3

12

P

R

N

G

3

ACPR

VIV8

34

P

S

N

A

1

ACPR

VIV20

9

P

R

N

A

2

TF

62298

5

P

R

N

A

2

ACPR

60250

6

P

R

N

A

2

ACPR

60149

8

P

R

N

G

3

ACPR

VIV4

30

P

R

N

G

3

ACPR

VIV12

6

P

R

N

G

3

TF

62079

0.8

P

R

N

A

2

TF

VIV15

2

P

R

N

A

2

Reinfection or relapse

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Malaria Journal

ISSN: 1475-2875

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