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Figure 2 | Malaria Journal

Figure 2

From: Cytokine-associated neutrophil extracellular traps and antinuclear antibodies in Plasmodium falciparum infected children under six years of age

Figure 2

Giemsa- and DAPI-stained peripheral fingerprick blood smears from children 5 years old and younger presenting with uncomplicated malaria. (A) low magnification field of a control smear from a child presenting with fever but no detectable P. falciparum; (B) field showing neutrophil exhibiting toxic granulation and lack of a distinct nuclear membrane (arrowhead)and fibrous material (arrow); (C) field showing NET (arrow) and P. falciparum-infected erythrocyte with a young trophozoite (arrowhead); (D) higher magnification image of field from (C); (E) Fibrous aggregate interpreted to be a NET containing parasitized erythrocytes (arrows); (F) Fibrous aggregate interpreted to be a NET sequestering parasitized erythrocytes; (G) DAPI-stained aggregate resembling fibrous structures in D and E (arrowhead) and normal neutrophil (arrow); (H) DAPI-stained aggregate resembling fibrous structures in D and E; and (I) DAPI-stained aggregate resembling fibrous structure in F. Bars: A, C 100 μm; B, D-F, 10 μm.

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Malaria Journal

ISSN: 1475-2875

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