Levels of IL-10, IL-6, TNF, IFN-γ, TGF-β, and CRP in plasma or serum drawn from 21 children ≤ 5 years old infected with P. falciparum before (Pre-Rx) and 7 days after treatment with SP (Rx). Individual values (n = 21) are represented as box plots indicating the 25th, 50th, and 75th percentile (solid lines from bottom to top of box), the 90th and 10th percentile values (high and low error bars respectively), and the mean value (dotted line). Closed circles represent the two highest values (above 90th percentile). Open circles represent the two lowest values (below 10th percentile; two open circles are superimposed in the plots where only one open circle is apparent). Horizontal bars on x-axes represent the upper limit of the range for normal healthy individuals determined with each assay kit by the manufacturer.