Figure 4

Levels of IL-10, IL-6, TNF, IFN-γ, TGF-β, and CRP in plasma or serum drawn from 21 children ≤ 5 years old infected with P. falciparum before (Pre-Rx) and 7 days after treatment with SP (Rx). Individual values (n = 21) are represented as box plots indicating the 25^th, 50^th, and 75^th percentile (solid lines from bottom to top of box), the 90th and 10^th percentile values (high and low error bars respectively), and the mean value (dotted line). Closed circles represent the two highest values (above 90^th percentile). Open circles represent the two lowest values (below 10^th percentile; two open circles are superimposed in the plots where only one open circle is apparent). Horizontal bars on x-axes represent the upper limit of the range for normal healthy individuals determined with each assay kit by the manufacturer.