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Table 4 CQ Treatment failures by Day 28 (adjusted by genotyping), stratified by age group and study site

From: Assessment of the efficacy of antimalarial drugs recommended by the National Malaria Control Programme in Madagascar: Up-dated baseline data from randomized and multi-site clinical trials

CQ

No. of treatment failure/Total of Patients (%) [95% CI]

  

0.5 – 4 years

≥ 5 years

All age

Tropical

Maevatanana

19/28 (67.9) [49.1–83.0]

9/24 (37.5) [20.1–57.8]

28/52 (53.8) [40.3–67.0]

 

Miandrivazo

10/16 (62.5) [37.6–83.2]

16/50 (32.0) [20.2–45.8]

26/66 (39.4) [28.2–51.5]

Highlands

Moramanga

10/26 (38.5) [21.5–57.9]

3/10 (30.0) [8.3–62.0]

13/36 (36.1) [21.8–52.6]

 

Tsiroanomandidy

13/21 (61.9) [40.2–80.5]

9/17 (52.9) [29.7–75.2]

22/38 (57.9) [41.9–72.7]

Sub-desert

Ejeda

14/20 (70.0) [47.7–86.8]

18/30 (60.0) [41.9–76.2]

32/50 (64.0) [50.1–76.4]

 

Ihosy

3/20 (15.0) [4.0–35.6]

8/38 (21.1) [10.3–36.1]

11/58 (19.0) [10.4–30.6]

  1. CQ: Chloroquine. CI: Confidence Interval. Chi-square test for the comparison of two proportions