Figure 4

The effect of basal lamina components on the viability of P. berghei wild-type, PbCTRP-KO, and PbSOAP-KO oocysts. Three clones of Plasmodium berghei were cultured in the presence or absence of Matrigel. -MAT = no Matrigel; +MAT = with Matrigel; WT = P. berghei ANKA clone 2.34; CTRP-KO = P. berghei CTRP-KO; SOAP-KO = P. berghei SOAP-KO. There was a significant reduction in the number of viable oocysts with increasing time of culture (GLM: F_(2,1,2,2) = 117.32, P < 0.001).