Table 3 Analysis of biomarkers for disease severity using multinomial logistic regression
From: Plasma IP-10, apoptotic and angiogenic factors associated with fatal cerebral malaria in India
BIOMARKER | COMPARISON OF DIFFERENT GROUPS | ODDS RATIO ESTIMATE | LOWER CONFIDENCE LIMIT | UPPER CONFIDENCE LIMIT | P-VALUE |
|---|---|---|---|---|---|
log IL-1ra | CMNS:HC | 4.159 | 2.257 | 7.666 | <0.0001 |
| Â | CM:HC | 3.615 | 2.177 | 6.002 | Â |
| Â | MM:HC | 2.815 | 1.74 | 4.551 | Â |
log IL-8 | CMNS:HC | 1.596 | 0.922 | 2.762 | 0.0006 |
| Â | CM:HC | 2.542 | 1.636 | 3.952 | Â |
| Â | MM:HC | 1.815 | 1.214 | 2.712 | Â |
log IL-10 | CMNS:HC | 3.749 | 1.915 | 7.34 | <0.0001 |
| Â | CM:HC | 4.38 | 2.364 | 8.115 | Â |
| Â | MM:HC | 4.21 | 2.278 | 7.777 | Â |
log TNF-R1 | CMNS:HC | 2.23 | 1.342 | 3.706 | <0.0001 |
| Â | CM:HC | 1.541 | 1.259 | 1.887 | Â |
| Â | MM:HC | 1.406 | 1.176 | 1.682 | Â |
log TNF-R2 | CMNS:HC | 1.966 | 1.183 | 3.265 | 0.0003 |
| Â | CM:HC | 1.279 | 1.095 | 1.495 | Â |
| Â | MM:HC | 1.387 | 1.162 | 1.656 | Â |
log VEGF | CMNS:HC | 0.299 | 0.149 | 0.6 | <0.0001 |
| Â | CM:HC | 1.078 | 0.647 | 1.794 | Â |
| Â | MM:HC | 1.684 | 0.96 | 2.953 | Â |
log IP-10 | CMNS:HC | 2.724 | 1.71 | 4.337 | <0.0001 |
| Â | CM:HC | 1.889 | 1.401 | 2.547 | Â |
| Â | MM:HC | 1.391 | 1.061 | 1.823 | Â |
log MIP-1β | CMNS:HC | 2.901 | 1.419 | 5.932 | 0.0005 |
| Â | CM:HC | 3.78 | 2.038 | 7.013 | Â |
| Â | MM:HC | 3.244 | 1.763 | 5.968 | Â |
log PDGFbb | CMNS:HC | 0.76 | 0.555 | 1.042 | 0.1863 |
| Â | CM:HC | 0.799 | 0.618 | 1.035 | Â |
| Â | MM:HC | 0.755 | 0.584 | 0.975 | Â |
log sFas | CMNS:HC | 6.033 | 2.077 | 17.523 | 0.0021 |
| Â | CM:HC | 2.515 | 1.246 | 5.078 | Â |
| Â | MM:HC | 1.244 | 0.655 | 2.363 | Â |
log FasL | CMNS:HC | 6.914 | 2.678 | 17.848 | 0.0001 |
| Â | CM:HC | 1.883 | 1.261 | 2.812 | Â |
| Â | MM:HC | 1.964 | 1.303 | 2.959 | Â |