Figure 3

Alignment of the of Plasmodium spp . MRP NBDs. Alignment of predicted NBD1 (A) and NBD2 (B) amino acid sequences from Plasmodium spp. mrp genes were performed using the ClustalW algorithm with the Blosum matrix (all other parameters set as default). Amino acids with a 100% identity are shaded in red, 99–75% identity are in blue and 74–50% identity in yellow. Conserved Walker A, Q loop, the ABC motif, Walker B motifs as well D loop and H loop motifs are indicated above the corresponding sequence. Within the NBD1 there is a large non conserved region in NBD1 between the ABC motif and the Walker B and D loop containing region (from position 961 to 1110 in the multiple sequence alignment) which is not shown in this figure. For the complete multiple sequence alignment refer to Additional file 3.