Table 4 Genotype analysis of pfmdr 1 and pfcrt in reinfection vs. recrudescences after AL treatment
From: Therapeutic efficacy of artemether-lumefantrine in uncomplicated falciparum malaria in India
Genotype at Day 0 | Genotype at Day of failure | ||||
|---|---|---|---|---|---|
Isolate | Day failure | pfmdr1 | pfcrt | pfmdr1 | pfcrt |
Reinfection (n = 2) | |||||
1 | Day28 | Y 86 Y184S1032N1042D1246 | C72I 74 E 75 T 76 | N86Y184S1032N1042D1246 | C72M74N75T 76 |
2 | Day38 | N86Y184S1032N1042D1246 | C72 I 74 E 75 T 76 | N86F 184 S1032N1042D1246 | C72M74N75T 76 /C72 I 74 E 75 T 76 |
Recrudescence (n = 1) | |||||
1 | Day7 | Y 86 Y184S1032N1042D1246 | C72M74N75K76 | Y 86 Y184S1032N1042D1246 | C72M74N75K76 |