Stage-dependent mRNA expression of parasite antioxidant enzymes (A; B) and HSPs (C) in parasites growing in G6PD-deficient (Mediterranean variant) RBCs. Changes in mRNA expression were measured using qRT-PCR. For details, see legend to Figure 1 and Materials and methods. The results are presented as -fold increase over the mRNA level at early ring stage measured 13 h after reinfection using the 2-ΔΔCt method. Mean values ± SEM, vertical bars, n = 5–7. Significances vs ring stage levels are indicated with symbols p < 0.001 (***), p < 0.01 (**), p < 0.05 (*).