Marked differences in CRP genotype frequencies between the Fulani and sympatric ethnic groups in Africa

Malaria Journal

Table 4 Genotype and allele frequencies of the +1444 CRP C>T polymorphism (rs1130864) in the sympatric ethnic groups in Mali and Sudan

	Mali		Sudan
	Fulani (n = 166)	Non-Fulani (n = 165)	Fulani (n = 213)	Non-Fulani (n = 46)
Genotype frequency
CC	123 (74%)	130 (79%)	160 (75%)	32 (70%)
CT	41 (25%)	34 (20%)	47 (22%)	14 (30%)
TT	2 (1%)	1 (1%)	6 (3%)	0 (0%)
P-value	0.5		0.3
Allele frequency
C	0.86	0.89	0.86	0.85
T	0.14	0.11	0.14	0.15
P-value	0.3		0.7
Frequency of T-allele carriers ^a
T	43 (26%)	35 (21%)	53 (25%)	14 (30%)
Non-T	123 (74%)	130 (79%)	160 (75%)	32 (70%)
P-value	0.3		0.4

^a Frequency of individuals with or without at least one T-allele of the +1444 CRP polymorphism

ISSN: 1475-2875