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Table 3 OHCT (nM) inhibits growth of P. falciparum gametocytes*

From: Antimalarial activity of a cis-terpenone

OHCT
(Stage I and II)
Chloroquine
(Stage I and II)
OHCT
(Stage III and IV)
Chloroquine
(Stage III and IV)
(IC 50 ) 22 ± 3.4 394 ± 127.0 36 ± 9.0 944 ± 92.0
(IC 90 ) 174 ± 5.4 1520 ± 27.5 226 ± 49.3 2109 ± 85.2
  1. *IC50 and IC90 values (nM) represent the mean ± SE of duplicate experiments, each performed in duplicate (vehicle and 8 concentrations per experiment