From: Efficacy of sulphadoxine-pyrimethamine with or without artesunate for the treatment of uncomplicated Plasmodium falciparum malaria in southern Mozambique: a randomized controlled trial
Variable
Hazard ratio
95% CI
P
Treatment with AS/SP vs SP
0.2
0.1–0.6
0.004
Age > 7 years vs. age ≤ 7 years
0.3
0.1–0.9
0.033
Presence of a quintuple mutation vs. fewer mutations
3.2
1.3–7.5
0.009
Temperature Day 0 (°C)
1.5
1.1–2.2
0.020