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Table 5 Prevalence of mutations at codons 108, 51, 59 in dhfr, and of mutations at codons 437, 540 of dhps in the study in Boende, N = 102

From: Varying efficacy of artesunate+amodiaquine and artesunate+sulphadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in the Democratic Republic of Congo: a report of two in-vivo studies

 

N

%

95% CI

Dhfr

   

- Sensitive

3

2.9

0.6–8.3

- Single-mutant 108

2

2.0

0.2–6.9

- Doublemutant 108, 51

31

30.4

21.7–40.3

- Double-mutant 108, 59

4

3.9

1.1–9.7

- Triple mutant 108, 51, 59

62

60.8

50.6–70.3

    Mixte

44

43.1

33.4–53.3

    Pure

18

17.6

10.8–26.4

Dhps

   

- Sensitive

30

29.4

20.8–39.2

- Single

68

66.7

56.6–75.7

- Double mutation 437, 540

4

3.9

1.1–9.7

    Mixte

1

1.0

0.0–5.3

    Pure

3

2.9

0.6–8.3