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Table 5 Prevalence of mutations at codons 108, 51, 59 in dhfr, and of mutations at codons 437, 540 of dhps in the study in Boende, N = 102

From: Varying efficacy of artesunate+amodiaquine and artesunate+sulphadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in the Democratic Republic of Congo: a report of two in-vivo studies

  N % 95% CI
Dhfr    
- Sensitive 3 2.9 0.6–8.3
- Single-mutant 108 2 2.0 0.2–6.9
- Doublemutant 108, 51 31 30.4 21.7–40.3
- Double-mutant 108, 59 4 3.9 1.1–9.7
- Triple mutant 108, 51, 59 62 60.8 50.6–70.3
    Mixte 44 43.1 33.4–53.3
    Pure 18 17.6 10.8–26.4
Dhps    
- Sensitive 30 29.4 20.8–39.2
- Single 68 66.7 56.6–75.7
- Double mutation 437, 540 4 3.9 1.1–9.7
    Mixte 1 1.0 0.0–5.3
    Pure 3 2.9 0.6–8.3