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Table 1 The frequency distribution of SNPs combinations of pvdhfr and pvdhps alleles associated with sulphadoxine/pyrimethamine in Plasmodium vivax isolates from north and southeastern, Iran

From: Molecular characterization of antifolates resistance-associated genes, (dhfr and dhps) in Plasmodium vivax isolates from the Middle East

Pvdhps

pvdhfr

   

A383G

A553G

I13L

P33L

F57I/L

S58R

T61M

S117T/N

I173L

South (%)

n = 143

North (%)

n = 46

Total (%)

n = 189

A

A

I

P

F

S

T

S

I

85 (59.4%)

39 (84.8%)

124 (65.6%)

A

A

I

P

F

S

T

N

I

26 (18.2%)

5 (10.8%)

31 (16.4%)

A

A

I

P

F

R

T

S

I

13 (9.1%)

1 (2.2%)

14 (7.4%)

A

A

I

P

F

R

T

N

I

17 (11.9%)

1 (2.2%)

18 (9.6%)

A

A

I

P

L

S

T

S

I

1 (0.7%)

-

1 (0.5%)

A

A

I

P

L

R

T

S

I

1 (0.7%)

-

1 (0.5%)

-

-

-

-

L = 1.1%

R = 17.5%

-

N = 26%

-