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Table 2 Specificity of antigen detection with rapid diagnostic tests compared to blood slide microscopy during follow-up.

From: Pf HRP2 and Pf LDH antigen detection for monitoring the efficacy of artemisinin-based combination therapy (ACT) in the treatment of uncomplicated falciparum malaria

Specificity

 

Pf LDH

Pf HRP2

 

%

95%CI

%

95%CI

D3

87.1 (141/162) ***

81.0 - 91.4

17.3 (28/162)

12.2 - 23.8

D7

92.0 (151/164) ***

86.9 - 95.3

29.9 (49/164)

23.4 - 37.3

D14

96.1 (150/156) ***

91.9 - 98.2

55.8 (87/156)

47.9 - 63.3

D21

96.5 (137/142) ***

92.1 - 98.5

73.2 (104/142)

65.4 - 79.8

D28

97.6 (122/125) ***

93.1 - 98.2

73.6 (92/155)

65.2 - 80.5

D35

97.6 (81/83) NS

91.6 - 99.3

95.2 (79/83)

88.2 - 98.1

D42

100.0 (77/77) NS

95.2 - 100.0

94.8 (73/77)

87.4 - 98.0

  1. ***: p < 0.0001; NS: p > 0.05