Skip to main content

Advertisement

Table 1 Baseline characteristics of patients in both treatment arms at the time of enrollment

From: Presumptive treatment with sulphadoxine-pyrimethamine versus weekly chloroquine for malaria prophylaxis in children with sickle cell anaemia in Uganda: a randomized controlled trial

Variable Treatment SP
N = 120
Treatment CQ
N = 122
Odds ratio 95% CI P- Value
Fever
Yes
No
26 (21.7%)
94 (78.3%)
24 (19.7%)
98 (80.3%)
1.129 0.06- 2.105 0.07
Joint pains
Yes
No
40 (38.3%)
80 (73.3%)
49 (40.2%)
73 (59.8%)
0.745 0.441-1.259 0.27
Headache
Yes
No
11 (9.2%)
109 (90.8%)
13 (10.7%)
109 (89.3%)
0.846 0.363-1.971 0.69
Drugs for malaria prophylaxis before the study
Yes
No
99 (48.3%)
21(56.8%)
106 (51.7%)
16 (43.2%)
0.712 0.351-1.441 0.89
Bed net use
Yes
No
77 (64.2%)
43 (35.8%)
98 (80.3%)
24 (19.7%)
0.44 0.23 -0.82 0.05
Pallor
Yes
No
115 (95.8%)
5 (4.2%)
115 (94.3%)
7 (5.7%)
1.4 0.432- 4.540 0.57
Jaundice
Yes
No
110 (91.7%)
10 (90.2%)
110 (90.2%)
12 (9.8%)
1.2 0.49 - 2.893 0.68
Age (yrs) mean (SD)
Age < 5 yrs
Age > 5 yrs
5.49 (4.5)
67 (55.8%)
53 (44.2%)
5.5 (4.3)
60 (49.2%)
62 (50.8%)
N/A
...
N/A
....
N/A
....
N/A
...
N/A
...
N/A
...
0.89
0.30
Sex
Female
Male
66(55%)
54(45.0%)
55(45.1%)
67(54.9%)
N/A
...
N/A
...
N/A
...
N/A
...
0.01*
Weight (kg) 18.43 ± 7.7 18.10 ± 6.8 N/A
...
N/A
...
0.72
Pulse (per min.) 92 ± 13.8 93 ± 15.0 N/A
...
N/A
...
0.58
Temperature(°C) 36.79 ± 2.0 36.5 ± 2.1 N/A
...
N/A
...
0.63
Haemoglobin (g/dl) 7.3 ± 1.29 7.2 ± 1.25 N/A
...
N/A
...
0.45
  1. * Values are numbers, percentage unless other wise stated; N/A - Not applicable