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Table 1 Baseline characteristics of patients in both treatment arms at the time of enrollment

From: Presumptive treatment with sulphadoxine-pyrimethamine versus weekly chloroquine for malaria prophylaxis in children with sickle cell anaemia in Uganda: a randomized controlled trial

Variable Treatment SP N = 120 Treatment CQ N = 122 Odds ratio 95% CI P- Value
Fever Yes No 26 (21.7%) 94 (78.3%) 24 (19.7%) 98 (80.3%) 1.129 0.06- 2.105 0.07
Joint pains Yes No 40 (38.3%) 80 (73.3%) 49 (40.2%) 73 (59.8%) 0.745 0.441-1.259 0.27
Headache Yes No 11 (9.2%) 109 (90.8%) 13 (10.7%) 109 (89.3%) 0.846 0.363-1.971 0.69
Drugs for malaria prophylaxis before the study Yes No 99 (48.3%) 21(56.8%) 106 (51.7%) 16 (43.2%) 0.712 0.351-1.441 0.89
Bed net use Yes No 77 (64.2%) 43 (35.8%) 98 (80.3%) 24 (19.7%) 0.44 0.23 -0.82 0.05
Pallor Yes No 115 (95.8%) 5 (4.2%) 115 (94.3%) 7 (5.7%) 1.4 0.432- 4.540 0.57
Jaundice Yes No 110 (91.7%) 10 (90.2%) 110 (90.2%) 12 (9.8%) 1.2 0.49 - 2.893 0.68
Age (yrs) mean (SD) Age < 5 yrs Age > 5 yrs 5.49 (4.5) 67 (55.8%) 53 (44.2%) 5.5 (4.3) 60 (49.2%) 62 (50.8%) N/A ... N/A .... N/A .... N/A ... N/A ... N/A ... 0.89 0.30
Sex Female Male 66(55%) 54(45.0%) 55(45.1%) 67(54.9%) N/A ... N/A ... N/A ... N/A ... 0.01*
Weight (kg) 18.43 ± 7.7 18.10 ± 6.8 N/A ... N/A ... 0.72
Pulse (per min.) 92 ± 13.8 93 ± 15.0 N/A ... N/A ... 0.58
Temperature(°C) 36.79 ± 2.0 36.5 ± 2.1 N/A ... N/A ... 0.63
Haemoglobin (g/dl) 7.3 ± 1.29 7.2 ± 1.25 N/A ... N/A ... 0.45
  1. * Values are numbers, percentage unless other wise stated; N/A - Not applicable