Figure 7From: Hyperparasitaemia and low dosing are an important source of anti-malarial drug resistanceSingle dose exposure to an artemisinin (arrow) results in a reduction in the number of sensitive parasites by a factor (the PRR) of 10,000 fold. But this is not enough to give a de-novo resistant parasites (red line) any chance of generating sufficient gametocytes for transmission as the sensitive sibling parasites (green lines) remain well ahead in the "race" to transmit.Back to article page