Skip to main content

Table 2 Association between placental malaria and low birth weight, stratified by maternal HIV status.

From: Placental malaria among HIV-infected and uninfected women receiving anti-folates in a high transmission area of Uganda

  Categories of placental malaria N Median birth weight (IQR) LBW (%) RR (95% CI)
Infants born to HIV- infected mothers on TS (n = 150) No Infection 120 3.10 (2.70-3.40) 13 (11) 1.0 (reference)
  PCR +/Smear - 21 2.90 (2.60-3.20)a 3 (14) 1.32 (0.41-4.23)
  Smear + 9 2.30 (2.20-3.00)b 5 (56) 5.13 (2.36-11.16)
Infants born to HIV- uninfected mothers on IPT-SP (n = 336) No Infection 249 3.10 (2.70-3.40) 25 (10) 1.0 (reference)
  PCR +/Smear - 57 2.80 (2.60-3.30)c 12 (21) 2.10 (1.12-3.92)
  Smear + 30 2.70 (2.50-3.00)d 7 (23) 2.32 (1.10-4.91)
  1. IQR = interquartile range; LBW = Low birth weight (birth weight < 2.50 kg); RR = Relative risk; 95% CI = 95 Percent confidence interval; TS = daily trimethoprim-sulphamethoxazole; IPT-SP = intermittent preventive therapy with sulphadoxine-pyrimethamine; PCR+/Smear-: placental malaria detected by PCR, but not by blood smear, Smear +: placental malaria detected by blood smear; Comparisons of relative risks of groups with 5 or fewer cases of placental malaria use Fisher's exact test, other comparisons use the chi-squared test.
  2. a p-value = .12 compared to infants born to HIV-infected mothers with no infection
  3. b p-value < .01 compared to infants born to HIV-infected mothers with no infection
  4. c p-value < .05 compared to infants born to HIV-uninfected mothers with no infection
  5. d p-value < .01 compared to infants born to HIV-uninfected mothers with no infection