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Table 4 Summary of neuropathological features in the brainstem of fatal severe malaria cases

From: Erythropoietin and its receptors in the brainstem of adults with fatal falciparum malaria

Neuropathological feature

 

Haemorrhages

(% severe cases, n = 20)

Astrogliosis

(% severe cases, n = 19)

Swollen Axons

(% severe cases, n = 20)

Chromatolysis

(% severe cases, n = 20)

Grade

NCM

CM

NCM

CM

NCM

CM

No. centres effected*

NCM

CM

0

40

20

15.8

26.3

20

10

1

25

10

1

0

10

36.8

15.8

15

10

2

10

10

2

0

15

0

5.3

15

30

3

15

25

3

10

5

0

0

0

0

4

0

5

  1. * All cases had at least 1 centre with chromatolytic neurons. Brainstem centres included: oculomotor, motor Vth, VIIth, vestibular, reticular formation and raphe, lateral cuneate, deep pontine and Xth [25].