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Table 3 Anti-P. falciparum IgG subclass and IgE levels (median) separated by IL4-590 CT genotype in patients with complicated and uncomplicated malaria (CM, UCM).

From: IL4 gene polymorphism and previous malaria experiences manipulate anti-Plasmodium falciparum antibody isotype profiles in complicated and uncomplicated malaria

  

CC

CT

TT

N

Median

N

Median

N

Median

P -value#

CM

       

Anti-Pf IgG1*

5

223.80

46

24.12

53

18.04

0.096

Anti-Pf IgG2*

5

6.05

46

2.03

53

2.79

0.112

Anti-Pf IgG3*

5

1.51

46

1.20

53

1.52

0.031

Anti-Pf IgE**

5

0.43

47

0.62

53

2.36

0.915

UCM

       

Anti-Pf IgG1*

11

252.80

67

39.32

84

88.21

0.195

Anti-Pf IgG2*

11

7.60

68

4.40

83

5.77

0.299

Anti-Pf IgG3*

11

2.65

68

2.69

85

3.13

0.622

Anti-Pf IgE**

11

0.96

68

0.65

85

0.76

0.892

  1. * = μg/ml, ** = ng/ml, N = number of patients, #Statistical analysis of differences
  2. in IgG subclass levels among the different genotypes tested with ANOVA.
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Malaria Journal

ISSN: 1475-2875

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