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Table 1 Allelic frequencies of TLR9 polymorphisms

From: TLR9 polymorphisms in African populations: no association with severe malaria, but evidence of cis-variants acting on gene expression

 

Gambia

Malawi

Controls1

Cases

Controls1

Cases

Case-control (n)

allele

628

883

416

712

TLR9 _rs187084

C

0.231

0.227

0.270

0.232

TLR9 _rs5743836

C

0.460

0.438

0.407

0.381

TLR9 _rs352139

A

0.395

0.413

0.396

0.444

TLR9 _rs352140_exonic

T

0.244

0.249

0.302

0.263

Trios (n)

 

2086

1043

376

188

TLR9 _rs187084

C

0.237

0.236

0.269

0.266

TLR9 _rs5743836

C

0.481

0.478

0.406

0.399

TLR9 _rs352139

A

0.435

0.418

0.378

0.391

TLR9 _rs352140_exonic

T

0.248

0.249

0.323

0.321

  1. 1 For the trios' cohort the parents were used as controls.
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Malaria Journal

ISSN: 1475-2875

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