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Table 1 Baseline characteristics of children enrolled in antimalarial in vivo efficacy study, Faladje, Mali.

From: Artemisinin-based combinations versus amodiaquine plus sulphadoxine-pyrimethamine for the treatment of uncomplicated malaria in Faladje, Mali

Characteristics

AS+AQ N = 133

AS+SP N = 132

AQ+SP N = 132

Mean age ± S.D. (months)

34.49 ± 15.97

36.08 ± 15.97

37.56 ± 16.07

Range

6–59

6–59

8–59

Male gender, n (%)

72 (54.1)

64 (48.8)

82(62.1)

Mean weight ± SD (kg)

12.76 ± 3.30

12.77 ± 3.42

13.21 ± 3.49

Range

6.30–23.70

6–19.6

7.70–21.7

Mean height ± SD (cm)

92.05 ± 12.88

92.86 ± 14.18

94.39 ± 14.12

Range

63–115

64–120

65–133

Mean axillary temperature ± SD(°C)

38.59 ± .77

38.52 ± .78

38.58 ± .76

Range

37.5–40.2

37.5–40.6

37.5–40.8

Palpable spleen, n (%)

38(28.6)

40(30.3)

49 (37.1)

Mean haemoglobin ± SD (g/dl)

9.83 ± 1.80

9.71 ± 1.67

9.98 ± 1.59

Haemoglobin < 11 g/dl, n (%)

93(69.9)

102(77.3)

97(73.5)

GMPD/μl

24,113.4

22,846.8

24,051.7

Prior antimalarial use, n (%)

11(8.3)

4(3)

7(5.3)

Disease duration <= 1 day, n (%)

83(62.4)

92(69.7)

80(60.6)

Gametocyte carriage n (%)

1(0.8)

8 (6.1)

1(0.8)

  1. AS+AQ, artesunate + amodiaquine; AS+SP, artesunate + sulphadoxine-pyrimethamine;
  2. AQ+SP, amodiaquine + sulphadoxine-pyrimethamine. S.D, Standard deviation:
  3. G/dl: Grams per deciliter
  4. GMPD/μl: Geometric Mean Parasite Density per microliter.
  5. P-values (not shown) were calculated from 2 × 3 X2 test, (for categorical variables) and by KruskalWallis test (for continuous variables with non-normal distributions). Groups were not statistically different, except for gametocyte carriage (p = 0.006).