Table 1 TLR2, 4, 9, and MAL mutant allele frequencies in various populations

Gene

Mutant allele

lowlands

lowlands

Highlands

African

Caucasian

Asian

TLR2

Δ22

0.131^I

0.298

0.326^II

0.215

0.131

0.256^VI

GTS

0.091

0.082

0.145

0.111

0.036

0.212

GTM

0.522^I

0.799

0.761

0.721

0.583

0.394^VI

GTL

0.387

0.120

0.094

0.168

0.381

0.394

Arg753Gln

0.000^V

0.000

0.000

0.011

0.038

0.000

TLR4

Asp299Gly

0.000^V

0.071^III

0.054^II

0.131

0.086

0.042

Thr399Ile

0.000^V

0.015

0.007

0.028

0.095

0.036

TLR9

-1486T/C

0.371^I

0.270

0.25^IV

0.343

0.340

0.361

-1237T/C

0.000

0.351

0.362

0.337

0.130

0.066

1174G/A

0.624^I

0.403

0.481^II

0.341

0.525

0.590

MAL

Ser180Leu

0.149

0.000

0.025

0.056

0.160

0.060^VI