Figure 1

Vaccination-induced protection against P. chabaudi malaria. BALB/c mice were vaccinated with ghosts from pRBC (+ vacc (pG); n = 18) or were not vaccinated (- vacc (untreated); n = 8) or were treated with ghosts from non-infected erythrocytes in FCA (nG; n = 8), or treated only with FCA (FCA; n = 17), before challenging with 10⁶ pRBC. All values are means and half standard errors of the mean (S.E.M.). **, p < 0.01, *, p < 0.05 vs. peak parasitaemia in vaccinated mice. The crisis phase (days 8–13 p.i.) is accentuated in grey.