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Figure 8 | Malaria Journal

Figure 8

From: Rate of red blood cell destruction varies in different strains of mice infected with Plasmodium berghei-ANKA after chronic exposure

Figure 8

Antibody level of the sera (1:40) from the semi-immune mice strains against white ghost RBC of an uninfected white ghost RBC. Sera were harvested in each of semi-immune mice strain at 7th cycle of infection (a) and at recovery (b), and (c) when both are compared. The antibody titer was measured via ELISA. Background values were not higher than 0.06 optical density (OD) units and those for control un-infected sera were slightly higher (mean 0.09). Antibody level in (a) and (b) expressed as individual plots, while the mean is represented by the horizontal bar within the individual plots. (a) **p < 0.001 when compared with the mean antibody titer of the other mice strains; *p < 0.05 when compared with CBA, Tukey's post-test. Balb/c, n = 10; B6, n = 11; NZW, n = 8; CBA, n = 12. (b) *p < 0.001 when compared with B6, CBA. Balb/c, n = 8; B6, n = 9; NZW, n = 7; CBA, n = 11, Normal, n = 9. (c) Error bars are standard error of the mean (SEM). One-way ANOVA was used to analyse data, p < 0.0001. ***/**/*p < 0.001, < 0.05, > 0.05 respectively when that at low Hb with infection is compared with that at recovery for each strain. Balb/c, n = 8; B6, n = 9; NZW, n = 7; CBA, n = 11. Results presented here are pooled data of two separate experiments, with duplicates.

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