1H NMR based OPLS-DA scores of urine of mice with/without infection with Plasmodium berghei ANKA. A. The model is from data of 6 uninfected mice of a litter (3 male, 3 female). Each point represents a sample corresponding to a mouse for the day indicated. The first number in the label indicates the mouse (1, 2 or 3); orange circle = male, green triangle = female. R2X (cum), Q2(cum) = 0.645, 0.811. B and C. Data from 3 mice (2 infected on day 7) of a litter monitored over 22 days, has been modeled in each case. Each point represents a mouse corresponding to the day indicated. The first number in the label indicates the mouse (1 = inf1, 2 = inf2, c = control). Black circle = uninfected, Red triangle = infected. R2X (cum), Q2(cum) are B. 0.632, 0.339, C. 0.73, 0.576. The ellipse is a 95% Hotelling's T2 ellipse.