Table 4 Malaria candidate-genes SNP associations based on case-control analysis in the two study sites (Sinnar and Rahad).
SNPs | Hausa vs control (N = 60/57) | Hausa + Massalit vs controls (N = 120/126) | Massalit vs Control (N = 60/69) | Abyay vs Nilotics (N = 67/53) | Sinnar Cases vs Controls (N = 125/78) | Sinnar vs combined (N = 58/78) | Sinnar vs Nilotics (N = 58/53) |
|---|---|---|---|---|---|---|---|
rs1050829 | NS | NS | p = 0.02 (0.17) | NS | NS | NS | NS |
rs1050828 | NS | NS | p = 0.04 (0.048) | NS | NS | NS | NS |
rs1800750 | NA | NA | NA | p < 2.2 × 10-16 (6.17 × 10-23) | P = 3.145 × 10-13 (4.9 × 10-24) | NS | NS |
rs3092945 | P = 0.05 (0.049) | P = 0.0025 (0.0074) | NS | p = 0.0091 (0.007) | 0.013 | P = 0.01 (0.35) | p = 0.01 (0.5) |
rs1805015 | NS | P = 0.0036 (0.032) | NS | P = 0.025 (0.022) | P = 0.065 (0.0080) | p = 0.001 (0.068) | p = 0.00018 (0.0044 |
rs2243250 | p = 0.04 | NS | NS | NS | NS | NS | NS |
rs17561 | NS | NS | NS | NS | p = 0.019 (0.156) | NS | NS |
rs708567 | NS | NS | NS | p = 0.022 (0.021) | NS | NS | P = 0.022 |
rs1800896 | NS | p = 0.036 (0.23) | p = 0.04 (0.28) | NS | NS | NS | NS |
rs17047661 | NS | NS | NS | NS | NS | p = 0.02 (0.89) | p = 0.00045 (0.0009) |
rs8386 | NA | NA | NA | p = 0.0040 (0.0021) | NS | NS | NS |
rs10775349 | NA | NA | NA | p = 0.013 (0.012) | p = 0.01216 (0.0034) | NS | NS |
rs2230739 | NA | NA | NA | p = 0.016 (0.0067) | NS | NS | NS |
rs8078340 | NA | NA | NA | p = 0.019 (0.016) | NS | NS | NS |