Figure 4
From: Plasmodium falciparum proteome changes in response to doxycycline treatment
Overview of metabolic pathways affected by doxycycline treatment in P. falciparum schizont stages adapted from Ginsburg, Hagai. ''Malaria Parasite Metabolic Pathways'' http://sites.huji.ac.il/malaria/. Metabolic pathways are indicated by boxes and metabolic steps by arrows. Up- and down-regulated proteins under DOX treatment are indicated in red and blue, respectively. Abbreviations: ALA, aminolevulinic acid; DOXP, deoxyxylulose phosphate; ER, endoplasmic reticulum; GA, Golgi apparatus; GA3P, glyceraldehydes-3-phosphate; GPI, glycosyl phosphatidylinositol; Hb, haemoglobin; PEP, phosphoenolpyruvate; PDH, phosphate dehydrogenase; PG, phosphoglycerate; PPT, phosphoenolpyruvate transporter; PYK, pyruvate kinase; TPT, triose phosphate transporter.