Table 3 Parascreen™ sensitivity, PPV and False-negative proportion at different parasitaemia determined by expert microscopy.
Parascreen™ | Parasite density (parasites/ul) | N (Number of samples) | Sensitivity [%(95%CI)] | PPV [%(95%CI)] | False - negative proportion [%(95%CI)] |
|---|---|---|---|---|---|
P. vivax | |||||
1-99 | 8 | 12.5 (2.2-47.1) | 100 | 87.5 (52.9-97.8) | |
100-499 | 15 | 60.0 (35.7-80.2) | 100 | 40.0 (19.8-64.3) | |
500-999 | 13 | 84.6 (57.8-95.7) | 100 | 15.4 (4.3-42.2) | |
1,000-4,999 | 35 | 91.4 (77.6-97.0) | 100 | 8.6 (3.0-22.4) | |
+ 5,000 | 12 | 91.7 (64.6-98.5) | 100 | 8.3 (1.5-35.4) | |
P. falciparum | |||||
1-999 | 5 | 25.0 (4.6-69.9) | 100 | 75.0 (30.1-95.4) | |
1,000-1,999 | 3 | 66.7 (20.8-93.9) | 100 | 33.3 (6.1-79.2) | |
2,000-4,999 | 4 | 75.0 (30.1-95.4) | 100 | 25.0 (4.6-69.9) | |
+ 5,000 | 3 | 66.7 (20.8-93.9) | 100 | 33.3 (6.1-79.2) |