Skip to main content

Table 2 Genotype abundance for uninfected and P. falciparum-infected molecular form A. gambiae associated with P. falciparum infection status.

From: Identification of three single nucleotide polymorphisms in Anopheles gambiae immune signaling genes that are associated with natural Plasmodium falciparum infection

Chromosome Gene Location Locus Genotype Mutation Type aM bS1 cS2
      dUI eI UI I UI I
3L 7,103,451-7,105,904 Ins34* CC synonymous 17 6 20 19 25 18
    CT synonymous 8 19 23 33 10 18
    TT synonymous 5 0 7 6 3 1
3L 8,174,795-8,178,377 Toll5B1* 1 CC synonymous 1 18 6 47 29 35
    TC synonymous 29 7 43 11 9 2
    TT synonymous 0 0 1 0 0 0
3L 8,174,795-8,178,377 Toll5B6* AA nonsynonymous 2 4 4 4 0 5
    AG nonsynonymous 5 2 18 3 13 12
    GG nonsynonymous 23 19 28 51 25 20
3L 7,103,451-7,105,904 Ins351 CC nonsynonymous 27 17 40 45 37 35
    CT nonsynonymous 3 8 10 13 1 1
    TT nonsynonymous 0 0 0 0 0 1
3L 7,103,451-7,105,904 Ins32 AA synonymous 2 0 5 1 2 1
    AG synonymous 9 16 25 29 11 17
    GG synonymous 19 9 20 28 25 19
3L 7,103,451-7,105,904 Ins33 CC nonsynonymous 24 14 29 30 1 1
    CT nonsynonymous 5 11 20 25 10 9
    TT nonsynonymous 1 0 1 3 27 27
2R 36,863,007-36,864,732 Mkk43 AA synonymous 0 0 1 0 0 0
    AG synonymous 5 7 10 3 1 4
    GG synonymous 25 18 39 55 37 33
3L 8,174,795-8,178,377 Toll5B2 AA nonsynonymous 30 25 46 56 37 36
    AC nonsynonymous 0 0 4 2 1 1
    CC nonsynonymous 0 0 0 0 0 0
  1. Groups included M uninfected, M infected, S1 uninfected, S1 infected, S2 uninfected, S2 infected. aM forms collected in Doneguebougou, Selinkenyi, and Sidaribougou, bS forms collected in Bancomana, Doneguebougou, Selinkenyi and Sidaribougou, cS forms collected in Pimperena. dUninfected (UI); eInfected (I) with P. falciparum.
  2. *Significant association with infection status (p < 0.0014), numbers of individuals in bold. 1Significant difference in genotype frequencies between S1 and S2 (p < 0.0014).