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Table 7 Estimated diagnostic accuracy of RDT for malaria - attributable fever during the low and high transmission seasons

From: Accuracy of a rapid diagnostic test on the diagnosis of malaria infection and of malaria - attributable fever during low and high transmission season in Burkina Faso

Age   Febrile Malaria-attributable Not malaria-attributable SE SP PPV NPV
(years)   N TP (a) FN (b) FP (c) TN (d)     
Low transmission (dry) season
< 1 143 4.4 0.2 35.9 102.4 95 74 11 99.8
1 - 4 299 8.8 0.5 88.2 201.5 94 70 9 99.7
5 - 14 130 4.0 0.3 39.9 85.7 93 68 9 99.7
15+ 280 2.5 0.3 46.2 230.9 89 83 5 99.9
All 852 19.8 1.3 210.3 620.6 94 75 9 99.8
High transmission (rainy) season
< 1 159 113.6 3.3 25.5 16.7 97 40 82 84
1 - 4 504 293.2 7.7 130.2 72.9 97 36 69 90
5 - 14 275 113.4 4.0 99.6 58.1 97 37 53 94
15+ 379 45.7 1.4 74.4 257.4 97 78 38 99.4
All 1317 565.8 16.4 329.7 405.1 97 55 63 96
  1. N: number of febrile patients in each age-parasite density combination.
  2. TP, FN, FP, TN: expected number of true positives, false negatives, false positives and true negatives of the RDT for clinical malaria diagnosis among the N febrile cases in each age-parasite density combination. Estimates obtained from N, AF and Prob RDT + (see methods). Numbers presented are rounded to 1 decimal place; actual calculations based on a better numerical precision.
  3. SE, SP, PPV, NPV: estimated sensitivity, specificity, positive predictive value, negative predictive value of RDT for clinical malaria.