Average clinical scores of C57BL/6 mice infected with PbAus and administered artemisone or chloroquine monotherapy (A), or combination therapy (B). No significant difference in clinical score was seen during the ECM phase when comparing control, artemisone- and chloroquine-treated groups. In contrast, significantly lower scores were seen in mice treated with artemisone and chloroquine throughout the experiment. *p < 0.05, control vs. treated groups. Average values ± SD (error bars) are presented. Arrows represent injections.