Table 5 Model results for dhfr triple mutant genotype
| Variable | Estimate | Std. Error | P-value |
|---|---|---|---|
| Year | 0.33 | 0.04 | < 0.01 |
| Type | |||
| Survey | Referent | - | - |
| Clinical | -0.13 | 0.03 | 0.66 |
| Age Category | 0.66 | ||
| Adolescents and adults | Referent | - | - |
| Children and adolescents | 0.05 | 0.43 | 0.91 |
| Children under 6 | 0.05 | 0.45 | 0.91 |
| Mixed ages | -0.37 | 0.50 | 0.46 |
| N/A | -0.43 | 0.53 | 0.41 |
| Mixed Mutants | 0.01 | ||
| Separate | Referent | - | - |
| Combined | 0.80 | 0.38 | 0.03 |
| Excluded | 1.11 | 0.40 | 0.01 |
| N/A | 0.21 | 0.32 | 0.50 |
| Random Effects | Variance | Std Dev | P-value |
| Country | 1.56 | 1.25 | < 0.01 |
| Study within Country | 0.89 | 0.94 | < 0.01 |