Table 2 Descriptive statistics of diagnostic accurary of neopterin, procalcitonin as compared with lactate for the diagnosis of severe falciparum malaria on admission.
| Â | Neopterin 95% Confidence Interval | Procalcitonin 95% Confidence Interval | Lactate 95% Confidence Interval | |||
|---|---|---|---|---|---|---|
Optimal cut-off value | 10 ng/ml | 0.9 ng/ml | 1.8 mmol/l | |||
Youden's index | 0.60 | Â | 0.53 | Â | 0.58 | Â |
Sensitivity | 0.93 | 0.64-1.00 | 1.00 | 0.70-1.00 | 0.92 | 0.60-1.00 |
Specificity | 0.67 | 0.54-0.78 | 0.53 | 0.40-0.66 | 0.66 | 0.51-0.78 |
Positive predictive value | 0.38 | 0.23-0.56 | 0.30 | 0.17-0.47 | 0.39 | 0.22-0.59 |
Negative predictive value | 0.98 | 0.86-1.00 | 1.00 | 0.87-1.00 | 0.97 | 0.83-1.00 |