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Table 2 Median values of antibody responses to varO-IE crude extract and varO recombinant domains, for healthy adults (HA) and children (AP, UM and SM, in 2006)

From: The humoral response to Plasmodium falciparum VarO rosetting variant and its association with protection against malaria in Beninese children

Antigens Median values (AU) a
HA (n = 30) AP (n = 52) UM (n = 37) SM (n = 65)
varO-IE crude extract IgG 95.6 (90.2-97.1) 86.6 (78.4-93.5) b 86.4 (69.7-90.1) c 72.2 (61.1-84.2)d, f, g
NTS-DBL1α 1 :
IgG 93.7 (88.9-99.5) 92.3 (74.0-105.9) 65.7 (61.9-79.9) c, e 64.4 (52.5-83.8) d, f
IgG1 nd 93.3 (82.2-99.3) 34.7 (21.6-50.1) e 37.0 (29.9-60.3) f
IgG3 nd 64.3 (42.9-80.2) 35.7 (27.4-46.8) e 46.3 (36.3-64.6) f, g
CIDRγ:
IgG 88.9 (63.6-103.4) 64.2 (49.7-100.9) 74.4 (53.3-107.3) 47.2 (39.3-52.4) d, f
IgG1 nd 83.5 (65.9-97.4) 75.1 (55.4-95.7) 65.1 (51.2-68.9) f
IgG3 nd 65.7 (51.4-81.0) 94.0 (64.2-107.0) 63.9 (45.7-70.0)
DL2βC2:
IgG 73.2 (59.4-90.4) 68.7 (47.0-82.2) 54.8 (43.4-70.8) 47.8 (37.6-68.3) d
IgG1 nd 93.3 (78.8-101.0) 82.8 (75.6-93.0) 81.9 (76.9-93.2)
IgG3 nd 64.2 (47.6-77.0) 48.2 (44.0-53.8) 69.8 (50.7-88.6)
  1. nd: not done
  2. a Median values (25th-75th percentiles), including responders only, and expressed in arbitrary units (AU).
  3. Significant differences (Mann-Whitney U-test, P < 0.05) between median values of HA and AP responders (b), HA and UM responders (c), HA and SM responders (d), AP and UM responders (e), AP and SM responders (f), and UM and SM responders (g).