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Table 2 Epidemiologic parameters considered in the analytic model, Amazon Region, Brazil, 2006.

From: Cost effectiveness of OptiMal® rapid diagnostic test for malaria in remote areas of the Amazon Region, Brazil

PARÂMETER BASE-CASE VALUE VARIATION VALUES INFORMATION SOURCES*
Prevalence of malaria among febrile patients seeking diagnosis (1) 24.6% 12.7% - 28.5% Base-case and variation: SIVEP/Malaria
Proportion of malaria cases due to Plasmodium vivax (1) 67.2% 63.6% - 92.4% Base-case and variation: SIVEP/Malaria
Proportion of malaria cases due to Plasmodium falciparum (1) 32.8% 7.6% - 36.4% Base-case and variation: SIVEP/Malaria
Sensitivity of microscopy for Plasmodium vivax 95% 77% - 82% Base-case: Ohrt et al., 2002
    Variation: Haghdoost et al.,2006; Iqbal et al., 1999
Specificity of microscopy for Plasmodium vivax 100% 95.0% -100.0% Base-case: Haghdoost et al.,2006
    Variation: Haghdoost et al.,2006
Sensitivity of microscopy for Plasmodium falciparum 92% 83% - 92% Base-case: Ohrt et al., 2002
    Variation: Humar et al., 1997
Specificity of microscopy for Plasmodium falciparum 100% 99% - 100% Base-case: Ndao et al., 2004
    variation: Humar et al., 1997
Sensitivity of OptiMal® for Plasmodium vivax 92% 62.5% -100% Base-case: PAHO Report, elaborated by Fontes, 2002
    Variation: Ratsimbasoa et al.,2007; Londoño et al., 2002
Specificity of OptiMal® for Plasmodium vivax 100% 80% - 100% Base-case: PAHO Report, elaborated by Fontes, 2002
    Variation: Londoño et al., 2002
Sensitivity of OptiMal® for Plasmodium falciparum 95.6% 62.3% - 98.8% Base-case: PAHO Report, elaborated by Fontes, 2002
    Variation: Palmer et al., 1998; OPAS Report, elaborated by Fontes, 2002
Specificity of OptiMal® for Plasmodium falciparum 99.6% 89.3% - 100% Base-case: PAHO Report, elaborated by Fontes, 2002
    Variation: Ferro et al.,2002; Ratsimbasoa et al.,2007
  1. Notes: * To the "Variation values", the first citation refers to the lowest value,
  2. and the second citation refers to the highest value.
  3. (1) The base-case values correspond to the values aggregated from 12 municipalities, and variation values correspond to the lowest and highest values found in the different risk strata presented in the 12 municipalities.