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Table 2 Epidemiologic parameters considered in the analytic model, Amazon Region, Brazil, 2006.

From: Cost effectiveness of OptiMal® rapid diagnostic test for malaria in remote areas of the Amazon Region, Brazil

PARÂMETER

BASE-CASE

VALUE

VARIATION

VALUES

INFORMATION

SOURCES*

Prevalence of malaria among febrile patients seeking diagnosis (1)

24.6%

12.7% - 28.5%

Base-case and variation: SIVEP/Malaria

Proportion of malaria cases due to Plasmodium vivax (1)

67.2%

63.6% - 92.4%

Base-case and variation: SIVEP/Malaria

Proportion of malaria cases due to Plasmodium falciparum (1)

32.8%

7.6% - 36.4%

Base-case and variation: SIVEP/Malaria

Sensitivity of microscopy for Plasmodium vivax

95%

77% - 82%

Base-case: Ohrt et al., 2002

   

Variation: Haghdoost et al.,2006; Iqbal et al., 1999

Specificity of microscopy for Plasmodium vivax

100%

95.0% -100.0%

Base-case: Haghdoost et al.,2006

   

Variation: Haghdoost et al.,2006

Sensitivity of microscopy for Plasmodium falciparum

92%

83% - 92%

Base-case: Ohrt et al., 2002

   

Variation: Humar et al., 1997

Specificity of microscopy for Plasmodium falciparum

100%

99% - 100%

Base-case: Ndao et al., 2004

   

variation: Humar et al., 1997

Sensitivity of OptiMal® for Plasmodium vivax

92%

62.5% -100%

Base-case: PAHO Report, elaborated by Fontes, 2002

   

Variation: Ratsimbasoa et al.,2007; Londoño et al., 2002

Specificity of OptiMal® for Plasmodium vivax

100%

80% - 100%

Base-case: PAHO Report, elaborated by Fontes, 2002

   

Variation: Londoño et al., 2002

Sensitivity of OptiMal® for Plasmodium falciparum

95.6%

62.3% - 98.8%

Base-case: PAHO Report, elaborated by Fontes, 2002

   

Variation: Palmer et al., 1998; OPAS Report, elaborated by Fontes, 2002

Specificity of OptiMal® for Plasmodium falciparum

99.6%

89.3% - 100%

Base-case: PAHO Report, elaborated by Fontes, 2002

   

Variation: Ferro et al.,2002; Ratsimbasoa et al.,2007

  1. Notes: * To the "Variation values", the first citation refers to the lowest value,
  2. and the second citation refers to the highest value.
  3. (1) The base-case values correspond to the values aggregated from 12 municipalities, and variation values correspond to the lowest and highest values found in the different risk strata presented in the 12 municipalities.