Table 2 Studies comparing HRP-2 performance between areas of different P. falciparum endemicity, using microscopy as a "gold standard".
Reference | Setting | Prevalence of positive blood smears in the study population (level of malaria transmission as reported by the author) | Sensitivity | Specificity |
|---|---|---|---|---|
Mharakurwa [24] | Zimbabwe | 10% (hypoendemic) | 91% | 92% |
| Â | Â | 40% (hyperendemic) | 95% | 85% |
| Â | Â | 59% (mesoendemic) | 93% | 72% |
Hopkins [17] | Uganda | 4% (hypoendemic) | na | 98% |
| Â | Â | 33 to 85% (hyperendemic) | na | 55% |
Mboera [14] | Tanzania | 4% (unstable, prone to outbreaks) | 92% | 99% |
| Â | Â | 14% (unstable, prone to outbreaks) | 97% | 97% |
| Â | Â | 22% (unstable, prone to outbreaks) | 84% | 91% |
| Â | Â | 49% (unstable, prone to outbreaks) | 98% | 90% |
| Â | Â | 46% (perennial) | 81% | 95% |
Abeku [25] | Tanzania | 1% (hypoendemic) | 90% | 100% |
| Â | Â | 49% (mesoendemic) | 91% | 65% |