Distinct patterns of blood-stage parasite antigens detected by plasma IgG subclasses from individuals with different level of exposure to Plasmodium falciparum infections

Table 1 Differential immunoblot pattern of low-molecular weight (< 70 kDa) parasite antigens detected by cytophilic antibodies

Plasma samples		Number of bands detected (Median and interquartile range)
Groups	Composition	IgG1	IgG3
A	Adult Danish travelers	5.0 (4.0-6.0)^c	6.0 (3.0 - 8.0)^f
B	Ghanaian children (0-5 yr)	5.5 (2.0-8.0)^b	4.0 (3.0 5.0)^e
C	Ghanaian children (6-10 yr)	6.5 (6.0-8.0)^a	8.5 (4.5 - 13.5)^d
D	Adult Liberians	9.0 (6.5-12.5)	14 (10.0 - 15.0)

Comparing IgG1 reactivity: ^a D vs. C, P = 0.121, D vs. B^b, P = 0.094, and D vs. A^c, P = 0.009. Comparing IgG3 reactivity: ^d D vs. C, P = 0.157, D vs. B^e, P = 0.006, and D vs. A^f, P = 0.010. P-values are based on Wilcoxons rank sum test with correction for ties.

ISSN: 1475-2875