Table 4 Lack of association between LTA/TNF/LTB SNPs and severe malaria subgroups when compared with adult and childhood controls in the Papuan population.
dbSNP rs | All CM (106)a | Adult SM (262) | Adult CM (85) | Childhood SM(118) | Childhood CM(21) | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Â | MAFb | P-value | MAF | P-value | MAF | P-value | MAF | P-value | MAF | P-value |
rs2857602 | 0.28 | 1.000 | 0.27 | 1.000 | 0.27 | 1.000 | 0.28 | 0.999 | 0.26 | 1.000 |
rs3131637 | 0.28 | 1.000 | 0.27 | 1.000 | 0.27 | 1.000 | 0.28 | 0.999 | 0.26 | 1.000 |
rs2844484 | 0.28 | 1.000 | 0.27 | 1.000 | 0.27 | 1.000 | 0.28 | 0.999 | 0.26 | 1.000 |
rs2844483 | 0.28 | 1.000 | 0.27 | 1.000 | 0.27 | 1.000 | 0.28 | 0.999 | 0.26 | 1.000 |
rs2009658 | 0.25 | 1.000 | 0.26 | 1.000 | 0.26 | 1.000 | 0.26 | 0.951 | 0.22 | 0.999 |
rs2844482 | 0.27 | 1.000 | 0.26 | 1.000 | 0.26 | 1.000 | 0.26 | 0.957 | 0.22 | 0.999 |
rs2071590 | 0.51 | 0.841 | 0.46 | 0.895 | 0.45 | 0.963 | 0.47 | 0.631 | 0.44 | 0.950 |
rs1800683 | 0.01 | 1.000 | 0.01 | 1.000 | 0.01 | 1.000 | 0.02 | 0.488 | 0.04 | 1.000 |
rs2239704 | 0.28 | 1.000 | 0.27 | 1.000 | 0.27 | 1.000 | 0.28 | 0.999 | 0.26 | 1.000 |
rs909253 | 0.01 | 1.000 | 0.01 | 1.000 | 0.01 | 1.000 | 0.02 | 0.488 | 0.04 | 1.000 |
rs2857713 | 0.27 | 1.000 | 0.26 | 1.000 | 0.26 | 1.000 | 0.26 | 0.983 | 0.23 | 1.000 |
rs1041981 | 0.01 | 1.000 | 0.01 | 0.999 | 0.01 | 1.000 | 0.02 | 0.488 | 0.04 | 1.000 |
rs1799964 | 0.27 | 1.000 | 0.26 | 1.000 | 0.26 | 1.000 | 0.26 | 0.951 | 0.22 | 0.999 |
rs1799724 | 0.36 | 0.597 | 0.41 | 0.992 | 0.41 | 0.869 | 0.41 | 0.744 | 0.45 | 0.992 |
rs1800610 | 0.36 | 0.902 | 0.40 | 1.000 | 0.40 | 0.945 | 0.41 | 0.828 | 0.44 | 0.996 |
rs3091257 | - | - | - | - | - | - | - | - | - | - |
rs769178 | 0.36 | 0.581 | 0.41 | 0.992 | 0.41 | 0.851 | 0.41 | 0.83 | 0.44 | 0.996 |
rs769177 | 0.06 | 0.983 | 0.04 | 1.000 | 0.04 | 1.000 | 0.05 | 1.00 | 0.06 | 0.995 |
rs1052248 | 0.50 | 0.490 | 0.45 | 0.543 | 0.44 | 0.878 | 0.46 | 0.26 | 0.40 | 0.884 |