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Table 2 Therapeutic responses of the enrolled children after treatment with AL or AA.

From: Early variations in plasmodium falciparum dynamics in Nigerian children after treatment with two artemisinin-based combinations: implications on delayed parasite clearance

Treatment groups

 

AL

AA

p-value

P↑ %

42

36.7

0.563

PRR 24 h

11 × 103

14 × 103

0.279

FCT (hours)

29.9 ± 18.4

28.9 ± 12.7

0.630

95% CI

26.83 - 32.82

25.81 - 31.93

 

PCT (hours)

28.6 ± 18.4

24.0 ± 15.4

0.067

95% CI

25.23 - 33.79

20.71 - 28.13

 

ETF

0

0

1.000

LPF

7.5%

7.8%

0.830

ACPR

92.5%

92.2%

0.830

PCR-corrected cure rates

93.5%

93.3%

0.955

  1. P↑ proportion with increase in peripheral blood parasitaemia in the first few hours of therapy
  2. PRR = parasite reduction ratio at 24 hours; FCT = fever clearance time;
  3. PCT = parasite clearance time; ETF = early treatment failure; LPF = late treatment failure
  4. ACPR = adequate clinical and parasitological response; Values are reported as mean ± SD or as proportions
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Malaria Journal

ISSN: 1475-2875

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