Table 3 Baseline parameters (at enrolment) between the two sub-groups of patients that showed different peripheral asexual parasitaemia in the immediate hours following administration of the first dose of treatment medications (all patient analysis, intention to treat population).
Parameters | Sub-group with no increase in peripheral asexual parasitaemia following onset of therapy | Sub-group with initial increase in peripheral asexual parasitaemia following onset of therapy |
|---|---|---|
Number (%) N = 193 | 118 (60.9%) | 75 (39.1%) |
Sex ratio M:F | 61:56 | 34:42 |
Mean age (years) ± SD | 6.6 ± 2.5 | 6.6 ± 2.7 |
95% CI | 4.71 - 7.72 | 5.01 - 8.72 |
Mean weight (kg) ± SD | 18.6 ± 5.1 | 18.7 ± 5.0 |
95% CI | 15.98 - 23.30 | 14.99 - 20.28 |
Mean duration of fever (days) ± SD | 2.7 ± 1.5 | 2.7 ± 1.1 |
95% CI | 1.98 - 3.87 | 1.74 - 3.89 |
Mean temperature (°C) ± SD | 38.3 ± 1.2 | 38.3 ± 1.2 |
95% CI | 37.78 - 39.13 | 38.18 - 39.74 |
Mean hematocrit (%) ± SD | 33.1 ± 3.6 | 32.1 ± 3.7 |
95% CI | 29.90-33.53 | 28.89 - 33.29 |
Geometric Mean of 0 hour parasitaemia | 82870 | 60437 |
Range | 2837 - 1105263 | 2657 - 1125000 |