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Figure 2 | Malaria Journal

Figure 2

From: Dynamic subcellular localization of isoforms of the folate pathway enzyme serine hydroxymethyltransferase (SHMT) through the erythrocytic cycle of Plasmodium falciparum

Figure 2

PfSHMTc immunofluorescence images showing localization in the mitochondrion. (A) Mid-trophozoite showing the association of a small mitochondrion with PfSHMTc fluorescence. (B) Early schizont showing association of an enlarged globular mitochondrion with a region of more intense PfSHMTc fluorescence. (C) Late schizont showing very little co-localization of mitochondria with areas of PfSHMTc fluorescence. Mitochondria are closely aligned to nuclei and show some co-localization with YOYO1 staining (scale bars 3 μm). The associated table shows the percentage volume (V%) and material (M%) co-localization data for PfSHMTc (Sc) and MitoTracker (MIT) fluorescence.

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Malaria Journal

ISSN: 1475-2875

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