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Table 3 Predictors of delay in parasite clearance at presentation in children with acute falciparum malaria
From: Factors contributing to delay in parasite clearance in uncomplicated falciparum malaria in children
| Variables | Number enrolled | PC >2 d | Crude OR (95% CI) | P Value | Adjusted OR (95% CI) | P Value |
|---|---|---|---|---|---|---|
| Age (years) | ||||||
| >2 | 2446 | 1076 | 1 | 1 | ||
| ≤ 2 | 267 | 140 | 1.40 (1.09 -1.80) | 0.008 | 2.13 (1.44 -3.15) | <0.0001 |
| Gender | ||||||
| Female | 1342 | 607 | 1 | |||
| Male | 1240 | 557 | 0.98 (0.84 -1.15) | 0.870 | - | - |
| Fever* | ||||||
| Absent | 686 | 252 | 1 | 1 | ||
| Present | 1743 | 842 | 1.6 (1.34 -1.93) | <0.0001 | 1.33 (1.04-1.69) | 0.019 |
| Duration of illness (d) | ||||||
| ≤ 3 | 2085 | 926 | 1 | |||
| > 3 | 521 | 246 | 1.12 (0.90 - 1.30) | 0.225 | - | - |
| Haematocrit (%) | ||||||
| ≥ 30 | 614 | 182 | 1 | |||
| <30 | 380 | 114 | 1.01 (0.76 - 1.34) | 0.904 | - | - |
| Parasitaemia (/μl blood) | ||||||
| ≤ 50,000 | 1607 | 634 | 1 | 1 | ||
| > 50,000 | 1145 | 603 | 1.70 (1.46 -1.99) | <0.0001 | 2.21 (1.77 - 2.75) | < 0.0001 |
| Gametocytaemia | ||||||
| Absent | 2086 | 896 | 1 | |||
| Present | 232 | 90 | 0.84 (0.63 - 1.10) | 0.224 | - | - |
| Vomiting | ||||||
| No | 1005 | 519 | 1 | 1 | ||
| Yes | 665 | 387 | 1.34 (1.07-1.58) | 0.009 | 1.21 (0.90-1.51) | 0.089 |
| Hepatomegaly | ||||||
| Absent | 471 | 237 | 1 | |||
| Present | 798 | 430 | 1.54 (0.91 - 1.44) | 0.219 | - | - |
| Year of enrolment | ||||||
| 2000 onward | 2165 | 872 | 1 | 1 | ||
| Before or 1999 | 587 | 365 | 2.43 (2.02 - 2.94) | 0.0.00 | 1.55 (1.22-1.96) | < 0.0001 |
