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Table 3 Predictors of delay in parasite clearance at presentation in children with acute falciparum malaria

From: Factors contributing to delay in parasite clearance in uncomplicated falciparum malaria in children

Variables Number enrolled PC >2 d Crude OR (95% CI) P Value Adjusted OR (95% CI) P Value
Age (years)       
   >2 2446 1076 1   1  
   ≤ 2 267 140 1.40 (1.09 -1.80) 0.008 2.13 (1.44 -3.15) <0.0001
Gender       
   Female 1342 607 1    
   Male 1240 557 0.98 (0.84 -1.15) 0.870 - -
Fever*       
   Absent 686 252 1   1  
   Present 1743 842 1.6 (1.34 -1.93) <0.0001 1.33 (1.04-1.69) 0.019
Duration of illness (d)       
   ≤ 3 2085 926 1    
   > 3 521 246 1.12 (0.90 - 1.30) 0.225 - -
Haematocrit (%)       
   ≥ 30 614 182 1    
   <30 380 114 1.01 (0.76 - 1.34) 0.904 - -
Parasitaemia (/μl blood)       
   ≤ 50,000 1607 634 1   1  
   > 50,000 1145 603 1.70 (1.46 -1.99) <0.0001 2.21 (1.77 - 2.75) < 0.0001
Gametocytaemia       
   Absent 2086 896 1    
   Present 232 90 0.84 (0.63 - 1.10) 0.224 - -
Vomiting       
   No 1005 519 1   1  
   Yes 665 387 1.34 (1.07-1.58) 0.009 1.21 (0.90-1.51) 0.089
Hepatomegaly       
   Absent 471 237 1    
   Present 798 430 1.54 (0.91 - 1.44) 0.219 - -
Year of enrolment       
   2000 onward 2165 872 1   1  
   Before or 1999 587 365 2.43 (2.02 - 2.94) 0.0.00 1.55 (1.22-1.96) < 0.0001
  1. CI, confidence interval; OR, odd ratio; PC, parasite clearance, *Body temperature ≥ 37.5°C