Comparison of the efficacy of AQ monotherapy, SP monotherapy, and AQ-SP combination in 3 sites during the 14-day follow-up period in 2003. Individual success rates (PCR uncorrected) are plotted. The horizontal line represents 95% confidence interval (CI) of each estimated proportion p, which is based on asymptotic normality. Black squares on each line denote the estimated proportion of adequate clinical and parasitological response (ACPR). The first dotted vertical line to the left corresponds to 75% of ACPR under which the treatment is considered as ineffective. The last 3 rows and their corresponding vertical lines refer to the global effect observed for sulphadoxine-pyrimethamine (SP; 88% ACPR), amodiaquine (AQ; 93% ACPR), and amodiaquine-sulphadoxine-pyrimethamine (AQ-SP; 94% ACPR), respectively.