Skip to main content

Table 1 Expected values for the observed infected proportion I(T), and person years at risk (PYAR) in a clinical trial with follow-up period T, of a vaccine with individual efficacy VE, in a region with force of infection Λ.

From: Heterogeneity in malaria exposure and vaccine response: implications for the interpretation of vaccine efficacy trials

Group

Proportion infected I(T)

Person years at risk PYAR

Control

1 - e-ΛT

Vaccine

1 - e-(1 - VE)ΛT