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Table 5 Structure-based comparison with PfNapL mutagenesis data

From: Structure, localization and histone binding properties of nuclear-associated nucleosome assembly protein from Plasmodium falciparum

 

PfNapL

PfNapS

Vps75

yNAP-1

hSET

Effect binding

    

1

I136

N112

S95

-

F115

2

I147

K120

S104

K230

R123

No effect on binding to PfNapL

PfNapS

Vps75

yNAP-1

hSET

1*

D192

E161

Q150

D278

S162

2

H227

E187

G181

N314

T191

3*

T230

T191

R184

D317

T194

4

Y259

P198

D198

Y342

D202

5*

E260

D199

S199

S343

E203

6*

K266

R205

S205

K349

K209

7

D223

W183

K177

E320

Disordered

  1. * conserved in PfNapS