Skip to main content


  • Oral presentation
  • Open Access

Refreshed approaches to the therapy of malaria - the case of natural medicine

  • 1
Malaria Journal20109 (Suppl 2) :O16

  • Published:


  • Infectious Disease
  • Malaria
  • Crude Extract
  • Malaria Parasite
  • Plasmodium Falciparum

Although the completion of genome project of the most virulent malaria parasite Plasmodium falciparum in 2002 evoked great hopes for the identification of new targets for novel drugs, these have not yet been fulfilled. This disappointment and the successful use of natural compounds emerging from traditional medicine for the chemotherapy of malaria (quinine, artemisnin) have invigorated the search for new antimalarials from natural sources. Hundreds of thousands compounds were screened and some promising leads were identified.

However, the great advantage of traditional medicine is a result of demonstrable synergism between the constituents of the crude extracts. The origin and the modes of action of this synergism will be discussed. In conclusion, it is suggested that greater emphasis should be given to traditional medicine and some considerations for its controlled implementation will be mentioned.

Authors’ Affiliations

Department of Biological Chemistry, Institute of Life Sciences, Hebrew University of Jerusalem, Jerusalem, Israel


© Ginsburg; licensee BioMed Central Ltd. 2010

This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate. Please note that comments may be removed without notice if they are flagged by another user or do not comply with our community guidelines.