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Figure 6 | Malaria Journal

Figure 6

From: Addition of histamine to subcutaneously injected Plasmodium berghei sporozoites increases the parasite liver load and could facilitate whole-parasite vaccination

Figure 6

In vivo liver load in relation to intravenously infected control animals. Mice were infected with 104 SPZ supplemented with either 3 μg histamine and 5 IU heparin sc (3 μg s.; n = 8) or 100 μg histamine and 5 IU heparin sc (100 μg sc; n = 8) or 100 μg histamine with (n = 4) or without (n = 4) 5 IU heparin im (mice are displayed combined in group 100 μg im; total n = 8). The intrahepatic flux was obtained at 48 hrs post-infection and is expressed in relation to the median flux measurement of four iv-infected control mice.

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