Figure 3From: A novel inhibitor of Plasmodium falciparum spermidine synthase: a twist in the tail A representation of the r-shaped Pf SpdS active site and its natural substrates, dcAdoMet and putrescine. The distances (Å) between the PhFs furthest apart and representative of the dimensions of the active site are shown. The shaded region of the active site indicates the DPM binding regions used in the virtual screen.Back to article page