Table 1 Results, sensitivity and specificity of LAMP (Pan and Plasmodium falciparum ) and RDT by screening site
Method | Positive no. | Negative no. | Sensitivity, % (95% CI) | Specificity, % (95% CI) |
|---|---|---|---|---|
Total | ||||
PCR | 18 (15 Pf, 1 Pm, 2 undetermined) | 978 | Reference | |
Pan-LAMP | 18 | 978 | 83.3 (58.6-96.4) | 99.7 (99.1-99.9) |
Pf-LAMP ¤ | 9 | 9 | 60.0 (32.3-83.7) | |
RDT | 10 | 996 | 55.6 (30.8-78.5) | 100 (99.6-100) |
Panga Tupu | ||||
PCR | 11 (9 Pf, 2 undetermined) | 260 | Reference | |
Pan-LAMP | 11* | 260 | 81.8 (48.2-97.7) | 99.2 (97.2-99.9) |
Pf-LAMP ¤ | 6 | 5 | 66.7 (29.9-92.5) | |
RDT | 5 | 266 | 45.5 (16.7-76.6) | 100 (98.6-100) |
Ukongoroni | ||||
PCR | 1 (Pf) | 421 | Reference | |
Pan-LAMP | 2 | 420 | 100 (2.5-100) | 99.8 (98.7-100) |
Pf-LAMP ¤ | 1 | 1 | 100 (2.5-100) | |
RDT | 1 | 421 | 100 (2.5-100) | 100 (99.1-100) |
Zingwezingwe | ||||
PCR | 6 (5 Pf, 1Pm) | 297 | Reference | |
Pan-LAMP | 5** | 298 | 83.3 (35.9-99.6) | 100 (98.8-100) |
Pf-LAMP ¤ | 2 | 4 | 40.0 (5.3-85.3) | |
RDT | 4 | 299 | 66.7 (22.3-95.7) | 100 (98.8-100) |